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Yes, its safety when used as a food additive has been approved by the U.S. Food and Drug Administration (FDA), Canada Health, European Food Safety Authority (EFSA), Joint FAO/WHO Expert Committee on Food Additives (JECFA), as well as other authorities.

FDA
It is permitted for direct addition to food for human consumption and may be used as an antimycotic on cheese in amounts not more than 20 mg/kg. (4)

By the way, FDA had no question on DSM’s conclusion that natamycin is Generally Recognized as Safe (GRAS) when used as an antimycotic to prevent the growth of molds and yeasts in ready-to-drink tea beverages, fruit-flavored beverages & energy drinks, and sport and isotonic drinks at levels not more than 0.5 mg/kg (5) AND in yogurt at levels not to exceed 5 ppm. (6)

Canada Health
It is permitted to used in preventing mould growth on the surfaces of cheeses with the maximum levels (7):

(naming the variety) cheese and cheddar cheese: 20ppm
Grated or shredded (naming the variety) cheese and grated or shredded cheddar cheese:10ppm
EFSA
Natamycin (E235) is listed in Commission Regulation (EU) No 231/2012 as an authorised food additive and categorized in “Additives other than colours and sweeteners” (8).

Evaluation in 2009
For the use of natamycin as a food additive, EFSA concluded that there was no safety concerns if only used in the surface treatment of the rind of semihard and semi-soft cheese and on the casings of certain sausages with the proposed use levels. Also, there was no concern for the induction of antimicrobial resistance. (9)

Authorised Uses And Use Levels
The following are the details for the uses and levels (10):

only for the external treatment of uncut hard, semi-hard and semi-soft ripened cheese and cheese products: at a maximum level of 1 mg/dm2 surface, not present at a depth of 5 mm.
only surface treatment of heat-treated (or not) dried cured sausages, at a maximum level of 1mg/kg.

http://www.chinafooding.com/Preservatives/

Sodium acid pyrophosphate white powder, relative density 1.86, insoluble in water, insoluble in ethanol, aqueous solution is heated with dilute acid hydrolysis of phosphoric acid, Sodium acid pyrophosphate hygroscopic, absorbing water to form six crystalline hydrate, Sodium acid pyrophosphate heated to above 220 ℃ partial decomposition of sodium.
Sodium acid pyrophosphate as fermentation agent, buffer, improvers, emulsifiers, nutrients, canned food preservatives, for baking food, Sodium acid pyrophosphate as a leavening agent in baked foods sodium sodium to control the fermentation speed, for instant noodles, reduce product time and avoid complex viscosity of water. Sodium acid pyrophosphate pastry for biscuits, shorten the fermentation time, reduce product breakage, loose gap neatly, Sodium acid pyrophosphate extended storage period. Sodium acid pyrophosphate packaging: 25 kg net paper bags or paper-plastic bags. Sodium acid pyrophosphate storage and transportation: Stored in dry, ventilated; Sodium acid pyrophosphate to prevent rain and moisture during transportation, loading and unloading should be with care, to prevent the packaging is damaged; stored separately from poisonous substances when.

http://www.chinafooding.com/Sodium_acid_pyrophosphate

Yes, its safety when used as a food additive has been approved by the U.S. Food and Drug Administration (FDA), European Food Safety Authority (EFSA), Joint FAO/WHO Expert Committee on Food Additives (JECFA), as well as other authorities.

FDA

SAPP is generally recognized as safe when used in accordance with good manufacturing practice (2) AND can be used as a color or coloring adjunct, dough strengthener, emulsifier or emulsifier salt, flavoring agent or adjuvant, flour treating agent, formulation aid, leavening agent, oxidizing or reducing agent, and sequestrant in food. (3)

EFSA
Disodium diphosphate (E450i) is listed in Commission Regulation (EU) No 231/2012 as an authorised food additive and categorized as “additives other than colours and sweeteners” (4)

Safety re-evaluation in 2019
In 2019, EFSA considered disodium pyrophosphate to be of low acute oral toxicity and there was no concern with respect to genotoxicity and carcinogenicity.

Also, no effects were reported in developmental toxicity studies. EFSA derived a group acceptable daily intake (ADI) for phosphates expressed as phosphorus of 40 mg/kg body weight (bw) per day and concluded that this ADI is protective for the human population.

Authorised Uses And Use Levels
Its application is listed in diphosphates E450 and the max uses level is 5000 (mg/l or mg/kg as appropriate).

The following foods may contain with it (5):

Processed fish and fishery products
Biscuits and rusks

http://www.chinafooding.com/Sodium_acid_pyrophosphate

As one chelating agent, it can be used in industrial cleaning, personal and household uses, Bleaching of pulp and textiles, Micronutrients for agriculture, Photo processing, Printing ink manufacturing , Food, Polymer processing and Metal plating etc.

http://www.chinafooding.com/EDTA

Yes, its safety when used as a food additive has been approved by the U.S. Food and Drug Administration (FDA), European Food Safety Authority (EFSA), Joint FAO/WHO Expert Committee on Food Additives (JECFA), as well as other authorities.

FDA
Calcium disodium EDTA may be safely used in following food categories for promoting color, flavor, texture retention or other functions with maximum levels ranging from 25 to 800 mg/kg (4):

Pickled cabbage and cucumbers
Canned carbonated soft drinks, fermented malt beverages
Canned white potatoes
Cooked canned of
Clams
Crabmeat
Dried lima beans
Legumes
Pink beans
Red beans
Mushrooms
Shrimp
French dressing, salad dressing, spreads, sauces
Mayonnaise, oleomargarine, pecan pie filling, potato salad
Processed dry pinto beans
Sandwich spread, artificially Colored and lemon-flavored or orange-flavored
Hard-cooked egg product
EFSA
Calcium disodium EDTA (E385) is listed in Commission Regulation (EU) No 231/2012 as an authorised food additive and categorized as “additives other than colours and sweeteners” (5)

http://www.chinafooding.com/EDTA